Completed Projects of the Junior Research Group Schwenk
Project "ENSuRE" - Exercise Nutrition Sarcopenia Review
Federal Ministry of Education and Research
The effect of exercise and nutritional intervention on sarcopenia-associated outcomes: a systematic review and meta-analysis
Current treatment strategies for sarcopenia include exercise and/or nutritional interventions. The ENSuRE project was funded from 2017 to 2019 via a research grant from the German Federal Ministry of Education and Research. The goal of this research was to provide a comprehensive overview of existing evidence on this topic by means of a systematic review and meta-analysis on the effects of such intervention programs on sarcopenia-associated outcomes. In cooperation with the Chair of Geriatric Medicine (Prof. Dr. med. Jürgen M. Bauer) and the Institute for Medical Biometry and Informatics (Dr. Katrin Jensen) of the Heidelberg University, we conducted a comprehensive synthesis and analysis of all available randomized controlled intervention studies on physical training and nutritional supplementation that concentrated on the amelioration of sarcopenia-associated endpoints. We included physiological parameters (muscle mass, strength, functional performance) as well as patient-relevant outcomes such as hospitalization, institutionalization, physical impairment and mobility. This work will help to find answers to the following specific questions:
* What role has physical training had on the treatment of sarcopenia?
* Which training interventions (type, dose) are most effective?
* What role does nutritional supplementation have on sarcopenia treatment?
* Which nutritional interventions (type, dose) are most effective?
* What additional benefits does a combination of both intervention types have when compared to interventions covering only one of the two domains?
Dr. Michael Schwenk, NAR, Heidelberg University (project lead)
Prof. Dr. med. M. Jürgen Bauer, AGAPLESION Bethanien Hospital Heidelberg
Dr. Kathrin Jensen, Institute for Medical Biometry and Informatics, Heidelberg University
Prof. Dr. Clemens Becker, Robert Bosch Hospital Stuttgart
Prof. Dr. Tommy Cedernholm, Uppsala University, Sweden