Projects of the Junior Research Group Schwenk

Project "LiFE-is-LiFE"


Federal Ministry of Education and Research


Introduce Lifestyle-integrated Functional Exercise (LiFE) to improve physical activity and reduce falls in older people: A multicenter non- inferiority trial comparison of a group-delivered and individually delivered Lifestyle-integrated Functional Exercise (LiFE) program in older people.

Project description:
The Lifestyle-integrated Functional Exercise (LiFE) program has proven effective in improving strength, balance, and physical activity while simultaneously reducing falls in older people via incorporation of exercises in recurring daily tasks. However, implementing the original LiFE program includes high financial obligations and human resources. Therefore, in LiFE-is-LiFE we investigate whether implementing LiFE in groups (gLiFE) is not inferior to the individually delivered iLiFE in terms of reducing falls via physical activity. Additionally, we expect gLiFE to be more cost-effective compared to iLiFE.
In the multicenter non-inferiority trial starting in 2018, 300 participants (> 70 years; confirmed fallers or with high fall risk) will be randomized in either iLiFE or gLiFE. Both groups will undergo the same strength and balance exercises and habitualization strategies as described in the LiFE programme, however, the delivery will be based on different approaches. In comparison to iLiFE, we expect gLiFE to (a) reduce falls per physical activity by a similar rate; (b) be more cost-effective; (c) comparably enhance physical performance in terms of strength and balance as well as physical activity. Regarding the non-inferiority margin, we will accept a 20% difference to the original LiFE as a comparable reduction.
Concerning the economic and societal benefit, this study is of high practical relevance as the non-inferiority of gLiFE would implicate facilitation of nationwide implementation due to lower financial and personnel requirements. In this way, the program would be better accessible to subjects who are at risk of having a fall.

Project partners:
Dr. Michael Schwenk, NAR, Heidelberg University
Dr. Carl-Philipp Jansen, NAR, Heidelberg University
Prof. Dr. Clemens Becker, Robert Bosch Hospital Stuttgart
PD Dr. Jochen Klenk, University of Ulm
Prof. Dr. Hans-Helmut König, University Hospital Hamburg-Eppendorf

Cooperation partners:
Prof. Dr. Lindy Clemson, University of Sydney
Prof. Hans-Werner Wahl, NAR, Heidelberg University
Prof. Dr. Lena Fleig, MBS, Medical School Berlin
Prof. Dr. Christopher James Todd, University of Manchester

Editor: Email
Latest Revision: 2021-04-16
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