NAR Lecture with Prof. Colin L. Masters on 29th October: Progress on the Road to Preventing Alzheimer´s Disease through Targeting the Amyloid Aß Pathway

On 29th October 2018, Prof. Colin L. Masters will hold a talk on Alzheimer’s disease at the NAR. He is currently the Co-Head of the Neurodegeneration Division of the Florey Institute of Neuroscience and Mental Health (Melbourne, Australia) and one of the world’s leading experts in the field of neurodegenerative disorders. Over the past 30 years, his research has been primarily focused on the pathology of Alzheimer’s, Creutzfeldt-Jakob, and Kuru diseases. In collaboration with Prof. Konrad Beyreuther Prof. Colin L. Masters has analysed the role of amyloid plaques in Alzheimer’s disease. Contact I Prof. Dr. Dr. h.c. Konrad Beyreuther Netzwerk AlternsfoRschung I Tel. +49 6221 54 6845



Association of Abnormal Serum Potassium Levels with Arrhythmias and Cardiovascular Mortality: a Systematic Review and Meta-Analysis of Observational Studies

Cardiovascular Drugs and Therap I 04.2018: Purpose To provide the first systematic review and meta-analysis of observational studies on the association of abnormal serumpotassium and cardiovascular outcomes. Methods Medline and ISI Web of Knowledge were systematically searched from inception until November 24, 2017. Data synthesis of relevant studies was performed using random effects model meta-analyses. Contact I Liesa Katharina Hoppe (Apothekerin) Doktorandin am Netzwerk AlternsfoRschung I Tel. +49 6221 54 8143



Potentially Inappropriate Medication Linked to Increased Mortality in Older Adults

JAMDA 01 March 2017: Potentially inappropriate medication (PIM) are drugs that pose unnecessarily high risk for older persons, as they are associated with an increased mortality of their users. This is the conclusion of a systematic review conducted by the junior research group led by Prof. Dr. Ben Schöttker. According to Clarissa Muhlack, the first author of the review and research associate at the NAR, the mortality of the study participants with PIM was 1.6 times higher than the mortality of those who did not take these medications. This association, however, has not yet been detected, as many studies contrarily did not show any influence of PIM on the mortality rate of older people. Yet, on a basis of a thorough analysis, the NAR researchers have succeeded to detect bias in these studies. “Our results underline once more that PIM should be avoided in older adults,” Clarissa Muhlack said. Written by I Clarissa Muhlack Junior Researcher at Network Aging Research I Tel. +49 6221 54 8143

Minipfeil Rotoriginal publication


23 February 2017

Mild cognitive impairment (MCI), a condition that often predates Alzheimer’s disease (AD), can be remotely detected through a self-administered virtual reality brain training game

JAD 20 February 2017: Thessaloniki, Greece, February 20, 2017 – Greek researchers demonstrated the potential of a self-administered virtual supermarket cognitive training game for remotely detecting mild cognitive impairment (MCI), without the need for an examiner,  among a sample of older adults. MCI patients suffer from cognitive problems and often encounter difficulties in performing complex activities such as financial planning. They are at a high risk for progressing to dementia however early detection of MCI and suitable interventions can stabilize the patients’ condition and prevent further decline. Contact I Stelios Zygouris Research Psychologist, PhD candidate I Aristotle University of Thessaloniki/ Network Aging Research




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